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PRODUCTION AND FORMULATION OF MONOCLONAL ANTIBODIES

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  • Production and Formulation of Monoclonal Antibodies
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Learning Outcomes

  • Define Structure and Functions of Antibodies
  • Compare antibody types, production in the body and mechanism of action
  • Identifies Polyclonal Antibodies (PoAb)
  • Identifies Monoclonal Antibodies (mAbs)
  • Compares Polyclonal Antibodies (PoAb) and Monoclonal Antibodies (mAbs). Defines the Hybridoma technology
  • List the technologies used in hybridoma production
  • List the technologies used in hybridoma production, explain the technologies used in hybridoma production one by one, explains the application areas of hybridoma technologies
  • Explains the production steps of polyclonal antibodies
  • Describes the production steps of monoclonal antibodies
  • Describes the characterization and purification processes of monoclonal antibodies, explain antibody production using recombinant dna technology, explain antibody production in plants and animals, knows the systems and culture environments used in antibody production
  • Gives examples of formulation studies with monoclonal antibodies in the literature
  • List the steps of Creating and Controlling Cell Banks
  • Explain the importance of media optimization in large-scale cell production
  • Outlines the upstream and downstream processes
  • Describes the Purification and Detection Methods of Monoclonal Antibodies
  • Explains the importance of validation of analytical methods for the formulation of monoclonal antibodies
  • List the used stability controls methods for the final product that prepared with monoclonal antibodies
  • Lists preclinical studies that used for trials of the final monoclonal antibodies formulations
  • Description
  • Content
  • Learning Outcomes
  • Learning Activities and Teaching Methods
  • Course's Contribution to Prog.
  • Assessment Methods
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