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MOLECULAR BIOLOGY

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Learning Outcomes

  • Will be able to explain DNA
  • Recognizes the structure of nucleotides and nucleosides.
  • Explains the synthesis of purine nucleotides.
  • Lists the synthetic inhibitors of purine synthesis
  • Lists the "salvage" pathways for purine recycling.
  • Explains the synthesis of deoxyribonucleotides.
  • Explains the degradation of purine nucleotides.
  • Explains purine synthesis and degradation.
  • Explains the structure of DNA.
  • Recognizes the forms of DNA.
  • Defines eukaryotic DNA replication.
  • Discusses DNA damage and repair mechanisms.
  • Will be able to explain RNA.
  • Explains the structure of RNA.
  • Lists the types of RNA.
  • Explains the steps of RNA synthesis.
  • Explains gene transcription.
  • Explains the post-transcriptional modifications of RNA.
  • Discusses the importance of protein synthesis for the organism.
  • Explains the genetic code.
  • Discusses the characteristics of the genetic code.
  • Explains the consequences of changes in nucleotide sequences.
  • Explains mRNA modifications.
  • Will be able to explain Translation and Transcription
  • Explains the entry of mRNA into the cytoplasm.
  • Lists the components required for translation.
  • Explains the process of translation.
  • Explains the structure of tRNA and how it recognizes codons.
  • Explains the steps of protein synthesis.
  • Explains the post-translational modifications of polypeptide chains.
  • Explains the transition of primary structure proteins through the endoplasmic reticulum.
  • Explains the further modifications of proteins in the ER.
  • Explains the factors that inhibit protein synthesis.
  • Will be able to explain gene expression in eukaryotes.
  • Explains the regulation of gene expression in eukaryotes.
  • Explains the organization of chromosomes in the nucleus.
  • Explains the organization of promoters.
  • Explains the steps of transcription in eukaryotes.
  • Explains post-transcriptional regulation in eukaryotes.
  • Will be able to explain gene expression disorders in eukaryotes
  • Explains gene expression disorders in eukaryotes.
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