PHARMACEUTICAL RAW MATERIALS I

Content

Weeks	Topics
1. Weeks	Definitions and history of pharmacognosy and pharmaceutical chemistry. Microscopic examination of powdered drugs. Introducing the necessary laboratory equipment for chemical synthesis.
2. Weeks	Cultivation , collection, drying, sorting, packaging, and storage of medical plants. Microscopic examination of powdered drugs. Classification of medicines according to thermodynamic activities. Synthesis applications.
3. Weeks	Pharmacognosy methods. Microscopic examination of powdered drugs. Chemical bonds in drug-receptor interaction. Synthesis applications.
4. Weeks	Biosynthesis in plants. Microscopic examination of powdered drugs. Drug-receptor compatibility and stereochemical factors. Synthesis applications.
5. Weeks	Primary metabolites; carbohydrates, oils, proteins and identification reactions. Structure-activity relationships. Synthesis applications.
6. Weeks	Secondary metabolites; glycosides (alcohol glycosides, cyanogenetic glycosides, anthracene glycosides, flavone glycosides, anthocyanins, coumarins, lignan glycosides) and diagnostic reactions. Structure-activity relationships. Qualitative analysis applications of some compounds with pharmaceutical importance.
7. Weeks	169/5000 Secondary metabolites; glycosides (steroid glycosides) and diagnostic reactions. The bioisoteres. Qualitative analysis applications of some compounds with pharmaceutical importance.
8. Weeks	Secondary metabolites; tannins, alkaloids and diagnostic reactions. Quantitative structure-activity relationships (QSAR). Qualitative analysis applications of some compounds with pharmaceutical importance.
9. Weeks	Secondary metabolites; isoprene derivatives, essential oils, resins and diagnostic methods. Quantitative structure-activity relationships (QSAR). Quantitative analysis applications of some compounds with pharmaceutical importance.
10. Weeks	Organic acids, alcohols, esters, waxes, hormones and diagnostic reactions. Drug structure and metabolism. Quantitative analysis applications of some compounds with pharmaceutical importance.
11. Weeks	Enzymes, antibiotics, biological products and their diagnostic reactions. Drug structure and metabolism. Quantitative analysis of some compounds with pharmaceutical importance.
12. Weeks	Biomedical methods in pharmacognosy; microbial biotransformation and applications. Drug design and new drug development. Separation and purification methods applied to synthetic and natural products and their applications.
13. Weeks	Drug design and new drug development. Separation and purification methods applied to synthetic and natural products and their applications.
14. Weeks	Combinatorial chemistry. Spectroscopic methods and applications applied to synthetic and natural products.