PHARMACEUTICAL RAW MATERIALS IV

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Learning Outcomes

Will be able to Evaluate Chemotherapeutic Drugs From a Chemical Point of View.
• Categories antiseptic and disinfectant drugs chemically. • Explains the chemical class of active substances. • Names antiseptic and disinfectant derivatives chemically. • Explains the chemical structure of antiseptic and disinfectant derivatives. • Explains the structure-activity relationships of antiseptic and disinfectant. • Explains the synthesis methods of antiseptic and disinfectant derivatives. • Categories antimycobacterials drugs chemically. • Explains the chemical class of active substances. • Names drug derivatives used in tuberculosis treatment. • Explains chemical structures of drug derivatives used in tuberculosis treatment. • Explains synthesis methods of drug derivatives used in tuberculosis treatment. • Names drug derivatives used in leprosy treatment. • Explains chemical structures of drug derivatives used in leprosy treatment. • Explains synthesis methods of drug derivatives used in leprosy treatment. • Categories sulfonamides drugs chemically. • Explains the chemical class of active substances. • Names sulfonamide derivatives. • Explains chemical structures of sulfonamide derivatives. • Explains the structure-activity relationships of sulfonamide derivatives. • Explains synthesis methods of sulfonamide derivatives. • Explains the biotransformation of sulfonamide derivatives. • Names folate reductase inhibitors. • Explains the chemical structure of folate reductase inhibitors. • Explains synthesis methods of folate reductase inhibitors. • Categories quinolones chemically. • Explains the chemical class of active substances. • Names quinolones derivatives. • Explains chemical structures of quinolones derivatives. • Explains the structure-activity relationships of quinolones derivatives. • Explains synthesis methods of quinolones derivatives. • Explains the biotransformation of quinolones derivatives. • Names oxazolidinone derivatives. • Explains the chemical structure of oxazolidinone derivatives. • Explains synthesis methods of oxazolidinone derivatives. • Categories nitroheterocyclic drug derivatives chemically. • Explains the chemical class of active substances. • Names nitroheterocyclic drug derivatives. • Explains the chemical structure of nitroheterocyclic drug derivatives. • Explains synthesis methods of nitroheterocyclic drug derivatives. • Categories antibiotics chemically. • Explains the chemical class of active substances. • Names penicillin derivatives. • Explains chemical structures of penicillin derivatives. • Explains the structure-activity relationships of penicillin derivatives. • Explain chirality in penicillin derivatives. • Explains synthesis methods of penicillin derivatives. • Explains the biotransformation of penicillin derivatives. • Names cephalosporin derivatives. • Explains chemical structures of cephalosporin derivatives. • Explains the structure-activity relationships of cephalosporin derivatives. • Explains synthesis methods of cephalosporin derivatives. • Names aminoglycoside derivatives. • Explains chemical structures of aminoglycoside derivatives. • Names tetracycline derivatives. • Explains chemical structures of tetracycline derivatives. • Explains the structure-activity relationships of tetracycline derivatives. • Explains synthesis methods of tetracycline derivatives. • Names macrolide antibiotic. • Explains chemical structures of macrolide antibiotic. • Explains synthesis methods of macrolide antibiotic. • Names polypeptide antibiotic derivatives. • Explains chemical structures of polypeptide antibiotic derivatives. • Names antibiotic derivatives of the lincosamide group. • Explains chemical structures of antibiotic derivatives of the lincosamide group. • Explains synthesis methods of antibiotic derivatives of the lincosamide group. • Names chloramphenicol group antibiotic derivatives. • Explains chemical structures of chloramphenicol group antibiotic derivatives. • Explains the structure-activity relationships of chloramphenicol group antibiotic derivatives. • Explains synthesis methods of chloramphenicol group antibiotic derivatives. • Names antibiotic derivatives of different structures. • Explains chemical structures of antibiotic derivatives of different structures. • Explains synthesis methods of antibiotic derivatives of different structures. • Categories antifungal derivatives chemically. • Explains the chemical class of active substances. • Names antifungal derivatives. • Explains chemical structures of antifungal derivatives. • Explains the structure-activity relationships of antifungal derivatives. • Explains synthesis methods of antifungal derivatives. • Explains the biotransformation of antifungal derivatives. • Categories antiviral derivatives chemically. • Explains the chemical class of active substances. • Names antiviral derivatives. • Explains chemical structures of antiviral derivatives. • Explains the structure-activity relationships of antiviral derivatives. • Explains synthesis methods of antiviral derivatives. • Explains the biotransformation of antiviral derivatives. • Categories anticancer derivatives chemically. • Explains the chemical class of active substances. • Names anticancer derivatives. • Explains chemical structures of anticancer derivatives. • Explains the structure-activity relationships of anticancer derivatives. • Explains synthesis methods of anticancer derivatives. • Explains the biotransformation of anticancer derivatives. • Categories antimalarial derivatives chemically. • Explains the chemical class of active substances. • Names antimalarial drugs derivatives. • Explains chemical structures of antimalarial derivatives. • Explains the structure-activity relationships of antimalarial derivatives. • Explains synthesis methods of antimalarial derivatives. • Explains the biotransformation of antimalarial derivatives. • Categories antiamibic derivatives chemically. • Explains the chemical class of active substances. • Names antiamibic drugs derivatives. • Explains chemical structures of antiamibic derivatives. • Explains the structure-activity relationships of antiamibic derivatives. • Explains synthesis methods of antiamibic derivatives. • Explains the biotransformation of antiamibic derivatives. • Categories drugs used in the treatment of Leishmania chemically. • Names drug derivatives used in Leishmania treatment. • Explains chemical structures of drug derivatives used in Leishmania treatment. • Explains synthesis methods of drug derivatives used in Leishmania treatment. • Names antitrichomonal drugs derivatives. • Explains chemical structures of antitrichomonal derivatives. • Explains synthesis methods of antitrichomonal derivatives. • Categories drugs used in the treatment of trypanazoma chemically. • Names drugs used in the treatment of trypanazoma. • Explains chemical structures of drugs used in the treatment of trypanazoma. • Explains synthesis methods of drugs used in the treatment of trypanazoma. • Names other antiprotozoal derivatives. • Explains chemical structures of other antiprotozoal derivatives. • Categories anthelmintic derivatives chemically. • Explains the chemical class of active substances. • Names anthelminticdrugs derivatives. • Explains chemical structures of anthelmintic derivatives. • Explains the structure-activity relationships of anthelmintic derivatives. • Explains synthesis methods of anthelmintic derivatives. • Explains the biotransformation of anthelmintic derivatives. • Categories drugs used against ectoparasites. • Explains the chemical class of active substances. • Names drug derivatives used against ectoparasites. • Explains chemical structure of drug derivatives used against ectoparasites. • Explains synthesis methods of drug derivatives used against ectoparasites
Will be able to Evaluate Herbal Drugs Related to Autonomic Nervous System.
• Lists the antibacterial drogs. • Describes the general characteristics of antibacterial drogs. • Explains the chemical composition of antibacterial drogs. • Explains the use and dosage of antibacterial drogs. • Explains the issues to be considered in the use of antibacterial drogs. • Lists the antiviral drogs. • Describes the general characteristics of antiviral drogs. • Explains the chemical composition of antiviral drogs. • Explains the use and dosage of antiviral drogs. • Explains the issues to be considered in the use of antiviral drogs. • Lists the antifungal drogs. • Describes the general characteristics of antifungal drogs. • Explains the chemical composition of antifungal drogs. • Explains the use and dosage of antifungal drogs. • Explains the issues to be considered in the use of antifungal drogs. • Lists the antiprotozoal drogs. • Describes the general characteristics of antiprotozoal drogs. • Explains the chemical composition of antiprotozoal drogs. • Explains the use and dosage of antiprotozoal drogs. • Explains the issues to be considered in the use of antiprotozoal drogs. • Lists the anthelmintic drogs. • Describes the general characteristics of anthelmintic drogs. • Explains the chemical composition of anthelmintic drogs. • Explains the use and dosage of anthelmintic drogs. • Explains the issues to be considered in the use of anthelmintic drogs. • Lists drogs. used against ectoparasites. • Describes the general characteristics of drogs used against ectoparasites. • Explains the chemical composition of drogs used against ectoparasites. • Explains the use and dosage of drogs used against ectoparasites. • Explains the issues to be considered in the use of drogs used against ectoparasites. • Lists effective drogs in cancer chemotherapy. • Describes the general characteristics of drogs used cancer chemotherapy. • Explains the chemical composition of drogs used cancer chemotherapy. • Explains the use and dosage of drogs used cancer chemotherapy. • Explains the issues to be considered in the use of drogs used cancer chemotherapy. • Lists immunomodulatory drogs. • Describes the general characteristics of immunomodulatory drogs. • Explains the chemical composition of immunomodulatory drogs. • Explains the use and dosage of immunomodulatory drogs. • Explains the issues to be considered in the use of immunomodulatory drogs.
Will be able to Evaluate Respiratory System Drugs From a Chemical Point of View.
• Categories antitussive drugs chemically. • Explains the chemical class of active substances. • Names opioid and other antitussive drug. • Explains chemical structures of opioid and other antitussive drug. • Explains the structure-activity relationships of opioid and other antitussive drug. • Explains synthesis methods of opioid and other antitussive drug. • Explains the biotransformation of opioid and other antitussive drug. • Names expectorant drug. • Explains chemical structures of expectorant drug. • Explains synthesis methods of expectorant drug. • Names mucolytic drug. • Explains chemical structures of mucolytic drug. • Explains synthesis methods of mucolytic drug. • Categories bronchodilator drugs and other anti-asthmatic drugs chemically. • Explains the chemical class of active substances. • Names betamimetic drug. • Explains chemical structures of betamimetic drug. • Explains synthesis methods of betamimetic drug. • Names phosphodiesterase derivatives. • Explains chemical structures of phosphodiesterase derivatives. • Names mast cell stabilizers. • Explains chemical structures of mast cell stabilizers.
Will be able to Evaluate Herbal Drugs Related to Respiratory System.
• Lists the antitussive drogs. • Describes the general characteristics of antitussive drogs. • Explains the chemical composition of antitussive drogs. • Explains the use and dosage of antitussive drogs. • Explains the issues to be considered in the use of antitussive drogs. • Lists the expectorant drogs. • Describes the general characteristics of expectorant drogs. • Explains the chemical composition of expectorant drogs. • Explains the use and dosage of expectorant drogs. • Explains the issues to be considered in the use of expectorant drogs. • Lists the mucolytically effective drogs. • Describes the general characteristics of mucolytically effective drogs. • Explains the chemical composition of mucolytically effective drogs. • Explains the use and dosage of mucolytically effective drogs. • Explains the issues to be considered in the use of mucolytically effective drogs. • Lists bronchodilator and antiastmatic drogs. • Describes the general characteristics of drogs with bronchodilator and antiastmatic effect. • Explains the chemical composition of drogs with bronchodilator and antiastmatic effect. • Explains the use and dosage of drogs with bronchodilator and antiastmatic effect. • Explains the issues to be considered in the use of drogs with bronchodilator and antiastmatic effect.
Will be able to Evaluate Quality Control Practices for Some Herbal Drugs; Synthesis, Analysis, Quality Control and Spectroscopy Practices of Some Pharmaceutical Compounds Related to Chemotherapeutics and Respiratory System.
• Determines the appropriate method for the synthesis of the target compound related to chemotherapeutics and respiratory system. • Explains synthesis method of target compound related to chemotherapeutics and respiratory system. • Explains the reaction equation and mechanism of the target compound related to chemotherapeutics and respiratory system. • Lists the chemicals required for the synthesis of the target compound related to chemotherapeutics and respiratory system. • Explains the properties of chemical substances and their intended use for the synthesis of the target compound related to chemotherapeutics and respiratory system. • Describes the properties and uses of devices required for synthesis of target compound related to chemotherapeutics and respiratory system. • Explains reaction conditions of synthesis of target compound related to chemotherapeutics and respiratory system. • Synthesizes the target compound related to chemotherapeutics and respiratory system. • Terminates the reaction of the target compound related to chemotherapeutics and respiratory system according to the result of the TAC application. • Applies the filtration process to remove the synthesis product related to chemotherapeutics and respiratory system from the reaction medium. • Applies extraction process to remove the synthesis product related to chemotherapeutics and respiratory system from the reaction medium. • Explains the physical and chemical properties of the synthesis product related to chemotherapeutics and respiratory system. • Calculates the theoretical, practical and percent yield of the synthesis product related to chemotherapeutics and respiratory system. • Determines the suitable recrystallization solvent for the synthesis product related to chemotherapeutics and respiratory system. • Describes recrystallization of the synthesis product related to chemotherapeutics and respiratory system. • Recrystallizes the synthesis product related to chemotherapeutics and respiratory system. • Lists the estimated IR data of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Determines which functional groups belong to the bands observed in the IR spectra of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Evaluates the structure by interpreting the IR spectra of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Lists the estimated 1H NMR data of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Determines the protons belong to the peaks observed in the 1H NMR spectra of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Specifies the structure by interpreting the 1H NMR spectra of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Lists the estimated MS data of pharmaceutical importance compounds related to chemotherapeutics and respiratory system. • Determines the parts belong to the peaks observed in the mass spectra of the compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Determines molecular ion peak in mass spectra of compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Determines the basic peak in the mass spectra of compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Interprets mass spectra of compounds of pharmaceutical importance related to chemotherapeutics and respiratory system. • Evaluates the structure of an unknown molecule by interpreting IR, NMR and Mass spectra and other techniques of pharmaceutical importance compounds related to chemotherapeutics and respiratory system. • The chemotherapeutics and respiratory system drug distinguishes the active substance sample by color, smell, taste and appearance. • Determines the melting point of the sample related to chemotherapeutics and respiratory system. • Determines the resolution class of sample related to chemotherapeutics and respiratory system. • Applies the burning test to the sample related to chemotherapeutics and respiratory system and interprets the results. • Determines the presence of nitrogen in the sample related to chemotherapeutics and respiratory system. • Detects the presence of sulfur in the sample related to chemotherapeutics and respiratory system. • Detects the presence of halogen in the sample related to chemotherapeutics and respiratory system. • Determines whether it is acidic, basic or neutral related to chemotherapeutics and respiratory system. • Distinguishes recognition tests of functional groups in the sample related to chemotherapeutics and respiratory system. • Explains the recognition tests of the functional groups in the sample related to chemotherapeutics and respiratory system. • Applies functional group recognition tests to the sample related to chemotherapeutics and respiratory system. • Identifies the specific diagnostic reaction that can be applied to the sample related to chemotherapeutics and respiratory system. • Performs a sample-specific diagnostic reaction. • Lists the titrimetric methods that can be applied to the sample related to chemotherapeutics and respiratory system. • Determines the purity of the sample related to chemotherapeutics and respiratory system by using the asymmetric method. • Determines the purity of the sample related to chemotherapeutics and respiratory system by using the alkalimetric method. • Determines the purity of the sample related to chemotherapeutics and respiratory system by using a nitriteometric method. • Determines the purity of the sample related to chemotherapeutics and respiratory system using the iodimetric method. • Detects the purity of the sample related to chemotherapeutics and respiratory system by spectrophotometric method specified in the pharmacopoeia.
Will be able to Evaluate Quality Control Practices for Some Herbal Drugs Related to Chemotherapeutics and Respiratory System.
• Applies macroscopic methods to a selected drog with antimicrobial effect. • Applies organoleptic methods to a selected drog with antimicrobial effect. • Evaluates the results of macroscopic and organoleptic analysis for a selected drog with antimicrobial effect. • List the appropriate reagents to examine a drog selected with antimicrobial effects by microscopic methods. • Uses the determination key to examine a selected drog with antimicrobial effect by microscopic methods. • Examines a selected drog with antimicrobial microscopically. • Interprets the microscopic examination results of a drog selected with antimicrobial effect. • Explains the foreign matter quantification method for a selected drog with antimicrobial effect. • Evaluates the results in terms of limit values by calculating the amount of foreign matter for a selected drog with antimicrobial effect. • Determines the appropriate method to determine the amount of water in a drog selected with antimicrobial effect. • Applies the appropriate method to determine the amount of water in a selected drog with antimicrobial effect. • Calculates the amount of water in a drog selected with antimicrobial effect and evaluates the results in terms of limit values. • Lists the physicochemical methods required for a selected drog with antimicrobial effect. • Explains the process steps of physicochemical methods for a selected drog with antimicrobial effect. • Determines the results of the physicochemical method required for a selected drog with antimicrobial effect. • Interprets the results of the physicochemical methods required for a drug selected with antimicrobial effect and compares it with the limit values. • Lists the appropriate extraction methods for target active substances in a selected drog with antimicrobial effect. • Applies the appropriate extraction method for the target active substances in a selected drog with antimicrobial effect. • Lists the appropriate diagnostic reactions for the target active substances in a selected drog with antimicrobial effect. • Evaluates the appropriate diagnostic reaction results for target active substances in a selected drog with antimicrobial effect. • Lists the appropriate chromatographic analysis methods for target active substances in a selected drog with antimicrobial effect. • Applies suitable chromatographic methods for target active substances in a selected drog with antimicrobial effect. • Evaluates the results of suitable chromatographic methods for target active substances in a selected drog with antimicrobial effect. • Determines the adulteration determinations specified in Pharmacopoeia for a drug with antimicrobial effect selected. • Determines adulterations in a selected drog with antimicrobial effect. • Interprets and evaluates all the results obtained for a selected drog with antimicrobial effect. • Applies macroscopic methods to a selected drog with chemotherapeutic effect. • Applies organoleptic methods to a selected drog with chemotherapeutic effect. • Evaluates the results of macroscopic and organoleptic analysis for a selected drog with chemotherapeutic effect. • List the appropriate reagents to examine a drog selected with chemotherapeutic effects by microscopic methods. • Uses the determination key to examine a selected drog with chemotherapeutic effect by microscopic methods. • Examines a selected drog with chemotherapeutic microscopically. • Interprets the microscopic examination results of a drog selected with chemotherapeutic effect. • Explains the foreign matter quantification method for a selected drog with chemotherapeutic effect. • Evaluates the results in terms of limit values by calculating the amount of foreign matter for a selected drog with chemotherapeutic effect. • Determines the appropriate method to determine the amount of water in a drog selected with chemotherapeutic effect. • Applies the appropriate method to determine the amount of water in a selected drog with chemotherapeutic effect. • Calculates the amount of water in a drog selected with chemotherapeutic effect and evaluates the results in terms of limit values. • Lists the physicochemical methods required for a selected drog with chemotherapeutic effect. • Explains the process steps of physicochemical methods for a selected drog with chemotherapeutic effect. • Determines the results of the physicochemical method required for a selected drog with chemotherapeutic effect. • Interprets the results of the physicochemical methods required for a drug selected with chemotherapeutic effect and compares it with the limit values. • Lists the appropriate extraction methods for target active substances in a selected drog with chemotherapeutic effect. • Applies the appropriate extraction method for the target active substances in a selected drog with chemotherapeutic effect. • Lists the appropriate diagnostic reactions for the target active substances in a selected drog with chemotherapeutic effect. • Evaluates the appropriate diagnostic reaction results for target active substances in a selected drog with chemotherapeutic effect. • Lists the appropriate chromatographic analysis methods for target active substances in a selected drog with chemotherapeutic effect. • Applies suitable chromatographic methods for target active substances in a selected drog with chemotherapeutic effect. • Evaluates the results of suitable chromatographic methods for target active substances in a selected drog with chemotherapeutic effect. • Determines the adulteration determinations specified in Pharmacopoeia for a drug with chemotherapeutic effect selected. • Determines adulterations in a selected drog with chemotherapeutic effect. • Interprets and evaluates all the results obtained for a selected drog with chemotherapeutic effect. • Applies macroscopic methods to an effective drog selected on the respiratory system. • Applies organoleptic methods to an effective drog selected on the respiratory system. • Interprets the results of macroscopic and organoleptic analysis for a drog chosen effectively on the respiratory system. • List the appropriate reagents to examine a drog selected on the respiratory system with microscopic methods. • Uses the determination key to examine a drog selected on the respiratory system with microscopic methods. • Examines a selected drog that is effectively selected on the respiratory system microscopically. • Interprets the microscopic examination results of a drog that is effectively selected on the respiratory system. • Explains the foreign matter quantification method for a selected drog that is effectively selected on the respiratory system. • Evaluates the results in terms of limit values by calculating the amount of foreign matter for a selected drog that is effectively selected on the respiratory system. • Determines the appropriate method to determine the amount of water in a drog that is effectively selected on the respiratory system. • Applies the appropriate method to determine the amount of water in a selected drog that is effectively on the respiratory system. • Calculates the amount of water in a drog that is effectively selected on the respiratory system and evaluates the results in terms of limit values. • Lists the physicochemical methods required for a drog that is effectively selected on the respiratory system. • Explains the process steps of physicochemical methods for a drog that is effectively selected on the respiratory system. • Determines the results of the physicochemical method required for a selected drog that is effectively selected on the respiratory system. • Interprets the results of the physicochemical methods required for a drug that is effectively selected on the respiratory system and compares it with the limit values. • Lists the appropriate extraction methods for target active substances in a drog that is effectively selected on the respiratory system. • Applies the appropriate extraction method for the target active substances in a drog that is effectively selected on the respiratory system. • Lists the appropriate diagnostic reactions for the target active substances in a drog that is effectively selected on the respiratory system. • Evaluates the appropriate diagnostic reaction results for target active substances in a drog that is effectively selected on the respiratory system. • Lists the appropriate chromatographic analysis methods for target active substances in a drog that is effectively selected on the respiratory system. • Applies suitable chromatographic methods for target active substances in a drog that is effectively selected on the respiratory system. • Evaluates the results of suitable chromatographic methods for target active substances in a drog that is effectively selected on the respiratory system. • Determines the adulteration determinations specified in Pharmacopoeia for a drog that is effectively selected on the respiratory system. • Determines adulterations in a drog that is effectively selected on the respiratory system. • Interprets and evaluates all the results obtained for a drog that is effectively selected on the respiratory system.